DESCRIPTION: 

Generalized inflammation of the oral mucosa of many possible etiologies

System(s) affected:

Skin/Exocrine

Genetics:

N/A

Incidence/Prevalence in USA:

• Herpetic stomatitis, hand-foot-and-mouth disease, and recurrent aphthous stomatitis are very common
• Herpangina is fairly common as are nicotinic and denture related stomatitis. The remaining causes are uncommon or rare.

Predominant age:

• Herpetic-primary infections - children
• Hand-foot-and-mouth disease - children
• Vincent's stomatitis - teenagers and young adults
• Behçet's disease - young adults
• Herpangina - children
• Others - N/A

Predominant sex:

Male = Female

CAUSES:

• Allergy - foods, drugs, contact (some erythema multiforme)
• Vitamin deficiency - riboflavin (angular stomatitis)
• Viral - herpes simplex I and II (herpetic stomatitis), Coxsackie A (herpangina and hand-foot-and-mouth disease)
• Smoking (nicotinic stomatitis)
• Hormonal (possibly recurrent ulcerative stomatitis)
• Uncertain (recurrent aphthous stomatitis, Vincent's stomatitis, recurrent scarifying stomatitis, Behçet's disease, angular stomatitis, gangrenous stomatitis, erythema multiforme)
•   Bacterial (scarlatina)
• Uremic (uremic/nephritic)
• Dentures